Endocrine Abstracts

Introduction: In order to detect the subjects at risk for osteoporotic fractures, one should actively search for them, primarily in a group of postmenopausal women, considering clinical risk factors. Body mass index (BMI) is a well-known, significant predictor of bone mineral density (BMD) of entire skeleton.Aim: The aim of this study was to examine relationship between BMI and BMD in a group of postmenopausal women.Methods: The st...

Introduction: Depression often occurs as comorbid and concomitant disorder in patients with type 2 diabetes (T2D) complicating the course and outcome of the disease, prolonging the treatment and accelerating complications of diabetes, especialy cardiovascular complications. Numerous researches show significant presence of cardiovascular disorders in depressed patients with T2D that show up several year after first depressive episode. Mortality caused by cardiovascular disorder...

Bone metabolism disorders in hemodialysed patients (HD) involve several humoral factors, of which PTH plays the central role. Leptin is a protein hormon secreted by the adipocytes and related to malnutrition, anemia and bone metabolism disorders in chronic kidney disease patients. The aim of the study was to was to evaluate serum leptin levels and bone metabolism in chronic HD patients depending on body mass index (BMI). This cross section study included 93 HD patients distrib...

Sixteen percent of parathyroid adenomas can be situated in an ectopic location. Ectopic parathyroid glands result from aberrant migration during early stages of development, and lack of successful identification may lead to lack of success in parathyroid surgery. These glands are most frequently found in the anterior mediastinum, in association with the thymus or the thyroid gland. Ectopic parathyroid glands are a major cause of persistent and recurrent hyperparathyroidism.</p...

Background: The partial or complete hypopituitarism is described as late complication of hemorrhagic fever with renal syndrome (HFRS). Imaging methods of pituitary gland examination in the chronic phase showed pituitary atrophy, but a precise pathogenic mechanism that causes pituitary damage in HRFS remains unclear. While hypopituitarism in HFRS is rarely described, cardiac failure as a known complication of hypopituitarism is even more rarely described. We present a case of s...

Introduction: There is a significant overlap of symptoms between polycystic ovary syndrome (PCOS) and thyroid disease, despite the fact that they are two different diseases. Both diseases individually affect a woman’s metabolic parameters and fertility, and their association makes them much more difficult to manage.Objective: To investigate the effect of elevated thyroid stimulating hormone (TSH) concentrations on metabolic and endocrine parameters ...

Introduction: Increased levels of high-sensitivity C-reactive protein (hs-CRP) and interleukin 6 (IL-6) accelerates atherosclerosis and occurrence of cardiovascular complications in patients with type 2 diabetes (T2D). Intima-media thickness (IMT) is a surrogate marker of atherosclerosis in patients with T2D.Aim: The aim of the study was to evaluate the significance of determining inflammatory markers IL-6, hs-CRP and IMT, as atherosclerosis markers, dur...

Introduction: Secondary failure (SF) to treatment with oral therapy is defined as the absence of a favorable reaction to the oral therapy which was effective in the previous course of the treatment. The aim of the work was to investigate the acute effects of the short-term insulin therapy on the secretory ability of endocrine pancreatic beta cells and the insulin resistance. Materials and Methods: 98 patients with diabetes mellitus type 2 (DM T2) and confirmed the SF to the or...

Introduction: Clinical assessment of atherosclerotic complications in type 2 diabetes mellitus (DM) was diverted to the detection of subclinical form of atherosclerosis using the non-invasive diagnostic methods. Surrogate markers of subclinical atherosclerosis are carotid intima-media thickness (IMT) and albuminuria. The aim of this study was to analyze a relationship between the presence of albuminuria and carotid IMT in patients with type 2 DM and silent ischemia.<p clas...

IntroductionDiabetes mellitus (DM) is considered as equivalent to cardiovascular disease (CVD), so the intensive control of all risk factors for CVD in patients with DM is recommended. Risk factors for CVD include: dyslipidemia, hypertension, smoking, family history of CVD and albuminuria. In addition to being a sensitive and reliable marker for evaluation of kidney function, research suggests that cystatin C may be a useful predictor for the detection a...